Archer™ FUSIONPlex™ Pan Solid Tumor v2 panel

Discover solid tumor insights with a pan-cancer RNA panel

Identify known and novel fusions, splice variants, single nucleotide variants, insertions, deletions, and relative RNA expression with targeted NGS of 137 genes relevant for colorectal, breast, melanoma, thyroid, gastric, pancreatic, CNS, NSCLC, sarcoma, and other cancer research.

Detect more with Archer FUSIONPlex NGS Panels for RNA.

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Product details

Panel specifications

Specifications
Targeted genes137
Genomic alterationsFusions, splicing, exon-skipping, SNVs, indels, expression
Input nucleic acid required*≥10 ng
Recommended number of reads3.5 M
Hands-on time≤3.5 hours
Total library prep time1.5 days
Platform compatibilityIllumina® and Ion Torrent™
Reagent formatLyophilized or liquid†
Supported sample typesFFPE, fresh frozen, cytology smear, FNA

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

†Liquid reagents available for Illumina platform only.

Gene targets

ACVR2A
AKT1
AKT2
AKT3
ALK
AR
ARHGAP26
ARHGAP6
AXL
BCOR
BRAF
BRD3
BRD4
CAMTA1
CCNB3
CCND1
CD274
CIC
CRTC1
CSF1
CSF1R
CTNNB1
DNAJB1
EGF
EGFR
EPC1
ERBB2
ERBB4
ERG
ESR1
ESRRA
ETV1
ETV4
ETV5
ETV6
EWSR1
FGF1
FGFR1
FGFR2
FGFR3
FGR
FOS
FOSB
FOXO1
FOXO4
FOXR2
FUS
GLI1
GRB7
HMGA2
HRAS
IDH1
IDH2
IGF1R
INSR
JAK2
JAK3
JAZF1
KIT
KRAS
MAML2
MAP2K1
MAST1
MAST2
MBTD1
MDM2
MEAF6
MET
MGEA5
MKL2
MN1
MSMB
MUSK
MYB
MYBL1
MYC
MYOD1
NCOA1
NCOA2
NCOA3
NFATC2
NFE2L2
NFIB
NOTCH1
NOTCH2
NR4A3
NRAS
NRG1
NTRK1
NTRK2
NTRK3
NUMBL
NUTM1
PAX3
PAX8
PDGFB
PDGFD
PDGFRA
PDGFRB
PHF1
PHKB
PIK3CA
PKN1
PLAG1
PPARG
PRDM10
PRKACA
PRKACB
PRKCA
PRKCB
PRKCD
PRKD1
PRKD2
PRKD3
RAD51B
RAF1
RELA
RET
ROS1
RSPO2
RSPO3
SS18
SS18L1
STAT6
TAF15
TCF12
TERT
TFE3
TFEB
TFG
THADA
TMPRSS2
USP6
VGLL2
WWTR1
YAP1
YWHAE

Interested in adding a few genes to this panel?

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Benefits

  • Detect more—Comprehensive fusion identification is enabled by open-ended targeted amplification, delivering detection of both novel and known fusions, while Archer Analysis's multifeatured pipeline provides data confidence and clear visualization of breakpoints.
  • Less QNSAnchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide variety of sample types, including low-input and potentially degraded samples such as FFPE tissue.
  • Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction‑sized lyophilized reagents or high‑throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.
  • Customize content—Use Assay Marketplace to modify any panel to fit your lab's needs or start from scratch to keep up with the pace of discovery.

Ready to start?

Talk with our technical sales team. Learn how the FUSIONPlex Pan Solid v2 panel can identify key genomic alterations for your research.

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Frequently asked questions

Related products

References

RUO23-2328_001