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Archer™ VARIANTPlex™ Core Myeloid panel

Unlock answers in myeloid-origin cancers with a targeted DNA panel

Identify key single nucleotide variants, insertions and deletions, copy number variations, and internal tandem duplications with targeted NGS of 37 core genes relevant for acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS), and lymphoid malignancies research.

Detect confidently with Archer VARIANTPlex NGS Panels for DNA.

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Learn how the VARIANTPlex Core Myeloid panel can identify key genomic alterations for your research.

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Product details

Panel specifications

Specifications
Targeted genes37
Genomic alterationsSNVs, Indels, CNVs, ITDs
Input DNA required*≥10 ng
Recommended number of reads3 M
Hands-on time<3.5 hours
Total library prep time1.5 day
Platform compatibilityIllumina®
Reagent formatLyophilized or liquid
Supported sample typesBlood, bone marrow, fresh frozen, BMMC, PBMC

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

Gene targets

ABL1
ANKRD26
ASXL1
BCOR
BRAF
CALR
CBL
CEBPA
CSF3R
DDX41
DNMT3A
ETNK1
ETV6
EZH2
FLT3
GATA1
GATA2
IDH1
IDH2
JAK2
KIT
KRAS
MPL
NPM1
NRAS
PHF6
PTPN11
RUNX1
SETBP1
SF3B1
SRSF2
STAG2
TET2
TP53
U2AF1
WT1
ZRSR2

Interested in adding a few genes to this panel?

Customize this NGS panel by adding any of our functionally-tested designs or create a new panel that fits your exact requirements with Assay Marketplace.

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Benefits

  • Detect confidently—A unique outlier detection algorithm leverages position-specific data to enable variant detection even at low allele frequencies, one of the many ways that Archer Analysis empowers you to detect confidently.
  • Less QNSAnchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and degraded samples such as FFPE tissue.
  • Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.
  • Customize content—Use Assay Marketplace to modify any panel to fit your lab’s needs or start from scratch to keep up with the pace of discovery.

Ready to start?

Talk with our technical sales team. Learn how the VARIANTPlex Core Myeloid panel can identify key genomic alterations for your research.

Request a consultation

Frequently asked questions

Related products

References

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