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Archer™ VARIANTPlex™ MPN Focus panel

Discover myeloid proliferative neoplasm insights with a targeted DNA panel

Identify key single nucleotide variants, insertions, deletions, copy number variations, and internal tandem duplications with targeted NGS of 12 genes relevant for myeloproliferative neoplasms (MPN) research.

Detect confidently with Archer VARIANTPlex NGS Panels for DNA.

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Learn how the VARIANTPlex MPN Focus panel can identify key genomic alterations for your research.

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Product details

Panel specifications

Specifications
Targeted genes12
Genomic alterationsSNVs, indels, ITDs
Input nucleic acid required*≥10 ng
Recommended number of reads800 K
Hands-on time<3.5 hours
Total library prep time1.5 days
Platform compatibilityIllumina®
Reagent formatLyophilized or liquid
Supported sample typesBlood, bone marrow, fresh frozen, FFPE, BMMC, PBMC

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

Gene targets

ASXL1
CALR
CSF3R
DNMT3A
EZH2
IDH1
IDH2
JAK2
KIT
MPL
SETBP1
TET2

Interested in adding a few genes to this panel?

Customize this NGS panel by adding any of our functionally-tested designs or create a new panel that fits your exact requirements with Assay Marketplace.

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Benefits

  • Detect confidently—A unique outlier detection algorithm leverages position-specific data to enable variant detection even at low allele frequencies, one of the many ways that Archer Analysis empowers you to detect confidently.
  • Less QNSAnchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and potentially degraded samples such as FFPE tissue.
  • Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.
  • Customize content—Use Assay Marketplace to modify any panel to fit your lab’s needs or start from scratch to keep up with the pace of discovery.

Ready to start?

Talk with our technical sales team. Learn how the VARIANTPlex MPN Focus panel can identify key genomic alterations for your research.

Request a consultation

Frequently asked questions

Related products

References

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