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Archer™ FUSIONPlex™ Heme v2 panel

Discover important heme onc insights with a targeted RNA panel

Identify known and novel fusions, splice variants, expression levels, single nucleotide variants, insertions, and deletions with targeted NGS of 87 genes relevant for hematological malignancy research.

Detect more with Archer FUSIONPlex NGS Panels for RNA.

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Product details

Panel specifications

Specifications
Targeted genes87
Genomic alterationsFusions, splicing, exon-skipping, SNVs, indels, expression levels
Input nucleic acid required*≥10 ng
Recommended number of reads1.5 M
Hands-on time<3.5 hours
Total library prep time1.5 days
Platform compatibilityIllumina® and Ion Torrent™
Reagent formatLyophilized or liquid†
Supported sample typesBlood, bone marrow, fresh frozen, FFPE, BMMC, PBMC

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

†Liquid reagents available for Illumina platform only.

Gene targets

ABL1
ABL2
ALK
BCL11B
BCL2
BCL3
BCL6
BCR
BIRC3
CBFB
CCND1
CCND2
CCND3
CD274
CDK6
CDKN2A
CEBPA
CEBPD
CEBPE
CEBPG
CHD1
CHIC2
CIITA
CREBBP
CRLF2
CSF1R
CTLA4
DEK
DUSP22
EBF1
EIF4A1
EPOR
ERG
ETV6
FGFR1
FOXP1
GLIS2
ID4
IKZF1
IKZF2
IKZF3
IRF4
IRF8
JAK2
KAT6A
KLF2
KMT2A
MALT1
MECOM
MKL1
MLF1
MLLT10
MLLT4
MUC1
MYC
MYH11
NF1
NFKB2
NOTCH1
NTRK3
NUP214
NUP98
P2RY8
PAG1
PAX5
PDCD1
PDCD1LG2
PDGFRA
PDGFRB
PICALM
PML
PRDM16
PTK2B
RARA
RBM15
ROS1
RUNX1
RUNX1T1
SEMA6A
SETD2
STIL
TAL1
TCF3
TFG
TP63
TYK2
ZCCHC7

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Benefits

  • Detect more—Comprehensive fusion identification is enabled by open-ended targeted amplification, delivering detection of both novel and known fusions, while Archer Analysis’s multifeatured pipeline provides data confidence and clear visualization of breakpoints.
  • Less QNSAnchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and degraded samples such as FFPE tissue.
  • Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.
  • Customize content—Use Assay Marketplace to modify any panel to fit your lab’s needs or start from scratch to keep up with the pace of discovery.

Ready to start?

Talk with our technical sales team. Learn how the FUSIONPlex Heme v2 panel can identify key genomic alterations for your research.

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Frequently asked questions

Related products

References

RUO23-2367_001